Pittcon Conference 2010

Middleton Research is presenting "Hyperspectral monitoring of moving pharmaceutical samples"

Abstract: Pharmaceutical, food and other industrial production samples have spatially non-uniform concentrations that need to be monitored for quality assurance and to improve the control of the processes. Hyperspectral push-broom spectral line-cameras are ideally suited for continuously moving industrial samples, producing full high resolution spectra of each point of a line at very high speed. Fully parallel spectral measurements of many points in a line at very high speed allows scanning moving samples, monitoring the whole surface. Optical arrangement of the hyperspectral cameras, the illumination and the sample can be, in most cases, diffuse reflectance or diffuse transmittance for solid samples or with samples having light scattering particles. In special cases, such as transparent samples or thin layer reflective samples, the arrangement could be direct transmission or close to specular reflectance angle. Measurement examples in the 1000-2500 nm wavelength region will be presented. Challenges and new measurement possibilities for the monitoring of pharmaceutical formulations, such as streams of tablets, webs and films will be discussed.

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